MicroRNA-224 Suppresses Colorectal Cancer Cell Migration by Targeting Cdc42
نویسندگان
چکیده
منابع مشابه
MicroRNA-224 Suppresses Colorectal Cancer Cell Migration by Targeting Cdc42
The metastatic spread of tumor cells is the major risk factor affecting the clinical prognosis of colorectal cancer (CRC) patients. The metastatic phenotype can be modulated by dysregulating the synthesis of different structural and functional proteins of tumor cells. Micro(mi)RNAs are noncoding RNAs that recognize their cognate messenger (m)RNA targets by sequence-specific interactions with th...
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MicroRNAs (miRs) are a type of small non-coding RNA molecule that are involved in gene silencing and the regulation of cancer progression; miR-133a in particular has been implicated in colorectal cancer, although its specific role and underlying mechanism have yet to be determined. In the present study, the expression level of miR-133a was significantly downregulated in a number of colorectal c...
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ژورنال
عنوان ژورنال: Disease Markers
سال: 2014
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2014/617150